Status of Biobased Production of Succinic Acid and Derivatives

The current status and future perspectives on the successful industrialization of biobased succinic acid are discussed in a comprehensive review article in the peer-reviewed journal Industrial Biotechnology

Succinic acid is one of the most important platform chemicals, with applications as a pharmaceutical ingredient, food additive, precursor of various chemicals, and raw material for biobased polymers. There is increasing demand for the sustainable production of succinic acid and its derivatives.

© Mary Ann Liebert, Inc.

Sang Yup Lee, from the Korea Advanced Institute of Science and Technology (KAIST), and coauthors, review the status of microbial succinic acid production, summarizing the titer, yield, and productivity achieved by various metabolically engineered microorganisms. They also discuss downstream processes for the purification of biobased succinic acid and showcase microbial production of several succinic acid derivatives of interest.

“This paper, submitted by Professor Sang Yup Lee, a highly distinguished innovator and pioneer in the field of systems metabolic engineering, is an excellent example of the cutting-edge science published by Industrial Biotechnology,” says Editor-in-Chief Richard A. Gross, PhD.

Click here to read the article now.

About the Journal

Industrial Biotechnology, led by Editor-in-Chief Richard A. Gross, PhD, Chair, Biocatalysts and Metabolic Engineering Constellation, Rensselaer Polytechnic Institute, is an authoritative journal focused on biobased industrial and environmental products and processes, published bimonthly in print and online. The Journal reports on the science, technology, business, and policy developments of the emerging global bioeconomy, including biobased production of energy and fuels, chemicals, materials, and consumer goods. The articles published include critically reviewed original research in all related sciences (biology, biochemistry, chemical and process engineering, agriculture), in addition to expert commentary on current policy, funding, markets, business, legal issues, and science trends. Industrial Biotechnology offers the premier forum bridging basic research and R&D with later-stage commercialization for sustainable biobased industrial and environmental applications.

About the Publisher

Mary Ann Liebert, Inc. is a global media company dedicated to creating, curating, and delivering impactful peer-reviewed research and authoritative content services to advance the fields of biotechnology and the life sciences, specialized clinical medicine, and public health and policy. For complete information, please visit the Mary Ann Liebert, Inc. website.


Mary Ann Liebert, press release, 2023-06-29.


Industrial Biotechnology Journal
Korea Advanced Institute of Science and Technology (KAIST)
Mary Ann Liebert, Inc. publishers


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