Method for biotechnological production of aminolevulinic acid via 1-precursor methanol

PROvendis, University of Bielefeld offering access to rights for commercial use and opportunity for further co-development

The technology enables the fast and competitive production of specific ALA via biotechnological process technology. The production of aminolevulinic acid (ALA) is the first step in the biosynthesis of tetrapyrroles and porphyrines (like Chlorophyll, vitamin B12, heme).

Recently ALA has attracted interest as a selective and biodegradable herbicide and insecticide. Besides ALA can be applied in the photodynamic therapy and treatment of various kinds of cancer. Administration of ALA in the tumorous tissue leads to a porphyrin formation inside the cells. Accumulated porphyrins generate reactive oxygene species when excited by light which can lead to death of the tumorous cell. On behalf of the University of Bielefeld, PROvendis offers access to rights for commercial use as well as the opportunity for further co-development.

Further information: PDF



Dipl.-Ing. Alfred Schillert
PROvendis GmbH
Phone: +49 (0)208/94105 10


About TechnologieAllianz

As Germany’s association of technology- and patenttransfer agencies TechnologieAllianz e.V. is offering businesses access to the entire range of innovative research results of almost all German universities and numerous non-university research institutions. More than 2000 technology offers of 14 branches are beeing made accessable to businesses in order to assure your advance on the market. At a free, fast and non-bureaucratic access to all further offers of the German research landscape is offered to our members aiming to sucessfully transfer technologies.


TechnologieAllianz, press release, 2016-09-19.


PROvendis GmbH
Universität Bielefeld