{"id":88626,"date":"2021-05-28T07:23:41","date_gmt":"2021-05-28T05:23:41","guid":{"rendered":"https:\/\/news.bio-based.eu\/?p=88626"},"modified":"2021-06-16T02:23:29","modified_gmt":"2021-06-16T00:23:29","slug":"dmcs-downstream-processing-proven-at-scale","status":"publish","type":"post","link":"https:\/\/renewable-carbon.eu\/news\/dmcs-downstream-processing-proven-at-scale\/","title":{"rendered":"DMC&#8217;s Downstream Processing Proven At Scale"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone  wp-image-88630\" src=\"https:\/\/renewable-carbon.eu\/news\/media\/2021\/06\/transparent-tank-rdme.png\" alt=\"transparent-tank-rdme\" width=\"554\" height=\"341\" \/><\/p>\n<p><strong>DMC Biotechnologies has completed downstream processing for its first product, the amino acid L-alanine. The downstream processing was done at EW Biotech in Leuna, Germany following the successful demonstration of commercial scale fermentation at the same site in\u00a0<a href=\"https:\/\/dmcbio.com\/press-releases\/dmc-demonstrates-full-commercial-scale-at-record-speed\" target=\"_blank\" rel=\"noopener\">March<\/a>.<\/strong><\/p>\n<p>The purification of L-alanine from the fermentation broth was successfully completed for more than 6,000 kg of product. Product release testing has demonstrated that rigorous customer specifications for L-alanine were met.<\/p>\n<p>Demonstration of the purification process and achievement of product specifications is the final proof point for DMC\u2019s approach to producing L-alanine. As announced on 21 April 2021, L-alanine is now available at commercial scale following execution of a\u00a0<a href=\"https:\/\/dmcbio.com\/press-releases\/dmc-and-conagen-partner-for-commercial-manufacturing-of-l-alanine\" target=\"_blank\" rel=\"noopener\">manufacturing agreement<\/a>\u00a0with Conagen.<\/p>\n<p>Matt Lipscomb, Ph.D., CEO &amp; Co-Founder of DMC said, \u201cWe recently announced the successful full commercial-scale demonstration of our fermentation process. Historically, fermentation scale-up has been a major stumbling block for early-stage companies. Delivering products to customers also requires successful purification and demonstration that the product meets the required specifications. We now have product with demonstrated quality metrics enabling customer adoption.\u201d<\/p>\n<p>Dr.-Ing. Markus Fritsch, Senior Project Manager at EW Biotech said, \u201cIt was a demanding project at a very unusual time.\u00a0\u00a0Preparations for the downstream processing (DSP) implementation in our facility went in parallel to the fermentation scale-up activities. With the deep contributions from our network of long-term partners we were able to deliver product that met target specifications. Thanks to DMC and our operating team at EW Biotech for making this project a joint success.\u201d<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone  wp-image-88629\" src=\"https:\/\/renewable-carbon.eu\/news\/media\/2021\/06\/EW_Biotech_Facility_2-1024x760.png\" alt=\"EW_Biotech_Facility_2\" width=\"574\" height=\"426\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>DMC Biotechnologies has completed downstream processing for its first product, the amino acid L-alanine. The downstream processing was done at EW Biotech in Leuna, Germany following the successful demonstration of commercial scale fermentation at the same site in\u00a0March. The purification of L-alanine from the fermentation broth was successfully completed for more than 6,000 kg of [&#8230;]<\/p>\n","protected":false},"author":59,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","nova_meta_subtitle":"","footnotes":""},"categories":[5572],"tags":[5838,5796,10408],"supplier":[15015,15828,18334],"class_list":["post-88626","post","type-post","status-publish","format-standard","hentry","category-bio-based","tag-bioeconomy","tag-biotechnology","tag-greenchemistry","supplier-conagen-inc","supplier-dmc-biotechnologies-inc","supplier-ew-biotech-gmbh"],"_links":{"self":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/88626","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/users\/59"}],"replies":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/comments?post=88626"}],"version-history":[{"count":0,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/88626\/revisions"}],"wp:attachment":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media?parent=88626"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/categories?post=88626"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/tags?post=88626"},{"taxonomy":"supplier","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/supplier?post=88626"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}