Synthetic methylotrophic yeasts possess advantageous properties and exploitable biotechnological potential.
\nMicrobial methylotrophy is a powerful and versatile pillar of a future circular bioeconomy.
\nUtilizing CCU-derived C 1 chemicals as a fermentation feedstock for climate-neutral bioprocesses offers various application potentials.
\nConnecting chemistry, electrochemistry, and bioengineering is the starting point to CO 2-based value chains.
\nThe development of synthetic methylotrophs is a key driver for the sustainable production of value-added chemicals and renewable fuels using CO 2 as an abundant resource.
\nYeasts cover vast product ranges (fatty acids, organic and amino acids, vitamins, modified proteins) and provide additional benefits over prokaryotes, such as their tolerance towards acidic conditions or their compartmentalization in organelles.<\/p>\n
Mitigating climate change is a key driver for the development of sustainable and CO 2-neutral production processes. In this regard, connecting carbon capture and utilization processes to derive microbial C 1 fermentation substrates from CO 2 is highly promising. This strategy uses methylotrophic microbes to unlock next-generation processes, converting CO 2-derived methanol. Synthetic biology approaches in particular can empower synthetic methylotrophs to produce a variety of commodity chemicals. We believe that yeasts have outstanding potential for this purpose, because they are able to separate toxic intermediates and metabolic reactions in organelles. This compartmentalization can be harnessed to design superior synthetic methylotrophs, capable of utilizing methanol and other hitherto largely disregarded C 1 compounds, thus supporting the establishment of a future circular economy.<\/p>\n","protected":false},"excerpt":{"rendered":"
Synthetic methylotrophic yeasts possess advantageous properties and exploitable biotechnological potential. Microbial methylotrophy is a powerful and versatile pillar of a future circular bioeconomy. Utilizing CCU-derived C 1 chemicals as a fermentation feedstock for climate-neutral bioprocesses offers various application potentials. Connecting chemistry, electrochemistry, and bioengineering is the starting point to CO 2-based value chains. The development […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","nova_meta_subtitle":"","footnotes":""},"categories":[5572,5571],"tags":[5838,5796,12330],"supplier":[11310],"class_list":["post-79948","post","type-post","status-publish","format-standard","hentry","category-bio-based","category-co2-based","tag-bioeconomy","tag-biotechnology","tag-ccu","supplier-cell-magazine"],"_links":{"self":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/79948","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/comments?post=79948"}],"version-history":[{"count":0,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/79948\/revisions"}],"wp:attachment":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media?parent=79948"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/categories?post=79948"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/tags?post=79948"},{"taxonomy":"supplier","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/supplier?post=79948"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}