{"id":79904,"date":"2020-10-16T06:44:00","date_gmt":"2020-10-16T04:44:00","guid":{"rendered":"https:\/\/rss.nova-institut.net\/public.php?url=https%3A%2F%2Fwww.cell.com%2Ftrends%2Fbiotechnology%2Ffulltext%2FS0167-7799%2820%2930241-9%3Frss%3Dyes"},"modified":"2020-10-15T12:21:16","modified_gmt":"2020-10-15T10:21:16","slug":"from-acetate-to-bio-based-products-underexploited-potential-for-industrial-biotechnology","status":"publish","type":"post","link":"https:\/\/renewable-carbon.eu\/news\/from-acetate-to-bio-based-products-underexploited-potential-for-industrial-biotechnology\/","title":{"rendered":"From Acetate to Bio-Based Products: Underexploited Potential for Industrial Biotechnology"},"content":{"rendered":"<p>The search for alternative carbon sources in industrial biotechnology is driven by the competing use of commonly used sugar-based substrates in the food and feed industry.<br \/>\nAcetate represents a highly attractive, alternative microbial carbon source for industrial biotechnology.<br \/>\nThe most interesting routes to alternatively generate acetate comprise the depolymerization of lignocellulosic materials and the Wood-Ljungdahl pathway of acetogenic bacteria to produce acetate as the main product via gas fermentation, microbial electrosynthesis, or microbial photosynthesis.<br \/>\nAcetate and acetate-containing streams have emerged as promising carbon sources for microorganisms to produce a variety of value-added bioproducts, such as platform chemicals (e.g., succinic acid), microbial lipids, bioplastics (e.g., polyhydroxyalkanoates), and biosurfactants (e.g., rhamnolipids).<\/p>\n<p>Currently, most biotechnological products are based on microbial conversion of carbohydrate substrates that are predominantly generated from sugar- or starch-containing plants. However, direct competitive uses of these feedstocks in the food and feed industry represent a dilemma, so using alternative carbon sources has become increasingly important in industrial biotechnology. A promising alternative carbon source that may be generated in substantial amounts from lignocellulosic biomass and C1 gases is acetate. This review discusses the underexploited potential of acetate to become a next-generation platform substrate in future industrial biotechnology and summarizes alternative sources and routes for acetate production. Furthermore, biotechnological aspects of microbial acetate utilization and the state of the art of biotechnological acetate conversion into value-added bioproducts are highlighted.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The search for alternative carbon sources in industrial biotechnology is driven by the competing use of commonly used sugar-based substrates in the food and feed industry. Acetate represents a highly attractive, alternative microbial carbon source for industrial biotechnology. The most interesting routes to alternatively generate acetate comprise the depolymerization of lignocellulosic materials and the Wood-Ljungdahl [&#8230;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","nova_meta_subtitle":"","footnotes":""},"categories":[5572],"tags":[5842,5796],"supplier":[11310],"class_list":["post-79904","post","type-post","status-publish","format-standard","hentry","category-bio-based","tag-biomass","tag-biotechnology","supplier-cell-magazine"],"_links":{"self":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/79904","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/comments?post=79904"}],"version-history":[{"count":0,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/79904\/revisions"}],"wp:attachment":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media?parent=79904"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/categories?post=79904"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/tags?post=79904"},{"taxonomy":"supplier","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/supplier?post=79904"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}