{"id":52688,"date":"2018-05-23T06:55:00","date_gmt":"2018-05-23T04:55:00","guid":{"rendered":"https:\/\/rss.nova-institut.net\/public.php?url=https%3A%2F%2Fwww.cell.com%2Ftrends%2Fbiotechnology%2Ffulltext%2FS0167-7799%2818%2930117-3%3Frss%3Dyes"},"modified":"2018-05-17T14:16:28","modified_gmt":"2018-05-17T12:16:28","slug":"overview-of-silk-fibroin-use-in-wound-dressings","status":"publish","type":"post","link":"https:\/\/renewable-carbon.eu\/news\/overview-of-silk-fibroin-use-in-wound-dressings\/","title":{"rendered":"Overview of Silk Fibroin Use in Wound Dressings"},"content":{"rendered":"<p>The growing field of tissue engineering has introduced remarkable wound dressings based on natural polymers.<\/p>\n<p>The unique properties of SF, such as its biocompatibility, biodegradability, high water and oxygen uptake, low immunogenicity, and robust mechanical properties, make it an exceptional choice for wound healing.<\/p>\n<p>Scaffolds containing different growth factors and signaling molecules are preferable for wound regeneration because they can interact with cells and consequently enhance cell behavior during the healing process.<\/p>\n<p>Despite the successful use of SF in wound dressings, it is not yet approved as an artificial skin.<\/p>\n<p>Recently, biomimetic wound dressings were introduced as potential replacements for treating skin injuries. Although there are some clinically available skin replacements, the range of wound types and locations necessitates a broader range of options for the clinic. Natural polymeric-based dressings are of central interest in this area due to their outstanding biocompatibility, biodegradability, low toxicity, and non-allergenic nature. Among them, silk fibroin (SF) has exceptional characteristics as a wound dressing. SF-based dressings can also be used as carriers for delivering drugs, growth factors, and bioactive agents to the wound area, while providing appropriate support for complete healing. In this review, we describe recent advances in the development of SF-based wound dressings for skin regeneration.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The growing field of tissue engineering has introduced remarkable wound dressings based on natural polymers. The unique properties of SF, such as its biocompatibility, biodegradability, high water and oxygen uptake, low immunogenicity, and robust mechanical properties, make it an exceptional choice for wound healing. Scaffolds containing different growth factors and signaling molecules are preferable for [&#8230;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","nova_meta_subtitle":"","footnotes":""},"categories":[5572],"tags":[14515,11270,11592],"supplier":[11310],"class_list":["post-52688","post","type-post","status-publish","format-standard","hentry","category-bio-based","tag-biocompatibility","tag-biodegradability","tag-polymers","supplier-cell-magazine"],"_links":{"self":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/52688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/comments?post=52688"}],"version-history":[{"count":0,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/52688\/revisions"}],"wp:attachment":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media?parent=52688"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/categories?post=52688"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/tags?post=52688"},{"taxonomy":"supplier","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/supplier?post=52688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}