{"id":39685,"date":"2017-01-11T07:35:26","date_gmt":"2017-01-11T06:35:26","guid":{"rendered":"https:\/\/renewable-carbon.eu\/news\/?p=39685"},"modified":"2021-09-09T21:39:18","modified_gmt":"2021-09-09T19:39:18","slug":"artificial-leaf-as-mini-factory-for-medicine","status":"publish","type":"post","link":"https:\/\/renewable-carbon.eu\/news\/artificial-leaf-as-mini-factory-for-medicine\/","title":{"rendered":"Artificial leaf as mini-factory for medicine"},"content":{"rendered":"<figure id=\"attachment_39687\" aria-describedby=\"caption-attachment-39687\" style=\"width: 480px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-39687 size-full\" src=\"https:\/\/renewable-carbon.eu\/news\/wp-content\/uploads\/2017\/01\/csm_BvOF_2016_1213_DX_license_TUe_-_artificial_leaf_for_organic_synthesis_04a7e58efc.jpg\" alt=\"artificial leaf for organic synthesis\" width=\"480\" height=\"320\" srcset=\"https:\/\/renewable-carbon.eu\/news\/media\/2017\/01\/csm_BvOF_2016_1213_DX_license_TUe_-_artificial_leaf_for_organic_synthesis_04a7e58efc.jpg 480w, https:\/\/renewable-carbon.eu\/news\/media\/2017\/01\/csm_BvOF_2016_1213_DX_license_TUe_-_artificial_leaf_for_organic_synthesis_04a7e58efc-300x200.jpg 300w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><figcaption id=\"caption-attachment-39687\" class=\"wp-caption-text\">Photo: TU Eindhoven \/ Bart van Overbeeke<\/figcaption><\/figure>\n<p><strong>To produce medicine sustainably and cheaply, anywhere you want. Whether in the middle of the jungle or even on Mars. A \u2018mini-factory\u2019 whereby sunlight can be captured to make chemical products. Inspired by the art of nature where leaves are able to collect enough sunlight to produce food, chemical engineers at Eindhoven University of Technology (TU\/e) have presented such a scenario. They describe their prototype reactor \u2013 consciously shaped as a leaf \u2013 in today\u2019s journal Angewandte Chemie.<\/strong><\/p>\n<p>Using sunlight to make chemical products has long been a dream of many a chemical engineer. The problem is that the available sunlight generates too little energy to kick off reactions. However, nature is able to do this. Antenna molecules in leaves capture energy from sunlight and collect it in the reaction centers of the leaf where enough solar energy is present for the chemical reactions that give the plant its food (photosynthesis).<\/p>\n<h3>Light capture<\/h3>\n<p>The researchers came across relatively new materials, known as luminescent solar concentrators (LSC\u2019s), which are able to capture sunlight in a similar way. Special light-sensitive molecules in these materials capture a large amount of the incoming light that they then convert into a specific color that is conducted to the edges via light conductivity. These LSC\u2019s are often used in practice in combination with solar cells to boost the yield.<\/p>\n<figure id=\"attachment_39686\" aria-describedby=\"caption-attachment-39686\" style=\"width: 480px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-39686 size-full\" src=\"https:\/\/renewable-carbon.eu\/news\/wp-content\/uploads\/2017\/01\/csm_BvOF_2016_1213_DR_license_TUe_-_artificial_leaf_for_organic_synthesis_2ae0100e25.jpg\" alt=\"artificial leaf for organic synthesis\" width=\"480\" height=\"320\" srcset=\"https:\/\/renewable-carbon.eu\/news\/media\/2017\/01\/csm_BvOF_2016_1213_DR_license_TUe_-_artificial_leaf_for_organic_synthesis_2ae0100e25.jpg 480w, https:\/\/renewable-carbon.eu\/news\/media\/2017\/01\/csm_BvOF_2016_1213_DR_license_TUe_-_artificial_leaf_for_organic_synthesis_2ae0100e25-300x200.jpg 300w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><figcaption id=\"caption-attachment-39686\" class=\"wp-caption-text\">Even with the naked eye the amount of light captured by the \u2018mini-factories\u2019 is visible, lit up bright red. The \u2018veins\u2019 through the leaves are the thin channels through which liquid can be pumped. The start products enter the one channel, light causes the reactions and the end product comes out via the other channels. Photo: TU Eindhoven \/ Bart van Overbeeke<\/figcaption><\/figure>\n<h3>Thin channels<\/h3>\n<p>The researchers, led by Dr. Timothy No\u00ebl, combined the idea of an LSC with their knowledge of microchannels, incorporating very thin channels in a silicon rubber LSC through which a liquid can be pumped. In this way they were able to bring the incoming sunlight into contact with the molecules in the liquid with high enough intensity to generate chemical reactions.<\/p>\n<h3>Surpassed<\/h3>\n<p>While the reaction they chose serves as an initial example, the results surpassed all their expectations, and not only in the lab. \u201cEven an experiment on a cloudy day demonstrated that the chemical production was 40 percent higher than in a similar experiment without LSC material\u201d, says research leader No\u00ebl. \u201cWe still see plenty of possibilities for improvement. We now have a powerful tool at our disposal that enables the sustainable, sunlight-based production of valuable chemical products like drugs or crop protection agents.\u201d<\/p>\n<h3>Paracetamol on Mars<\/h3>\n<p>For the production of drugs there is certainly a lot of potential. The chemical reactions for producing drugs currently require toxic chemicals and a lot of energy in the form of fossil fuels. By using visible light the same reactions become sustainable, cheap and, in theory, countless times faster. But No\u00ebl believes it should not have to stop there. \u201cUsing a reactor like this means you can make drugs anywhere, in principle, whether malaria drugs in the jungle or paracetamol on Mars. All you need is sunlight and this mini-factory.\u201d<\/p>\n<p>&nbsp;<\/p>\n<h3>Reference<\/h3>\n<p>D. Cambi\u00e9, F. Zhao, V. Hessel, M. G. Debije, T. No\u00ebl, A leaf-inspired luminescent solar concentrator for energy efficient continuous-flow photochemistry, Angewandte Chemie Int. Ed. (21 December 2016). DOI: <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201611101\/abstract\" target=\"_blank\" rel=\"noopener\">10.1002\/anie.201611101<\/a><\/p>\n<p>The article is labeled as a \u2018VIP publication\u2019, which means that the journal considers this to be an exceptional piece of work. Less than 5% of the publications in this magazine get such a label.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>To produce medicine sustainably and cheaply, anywhere you want. Whether in the middle of the jungle or even on Mars. A \u2018mini-factory\u2019 whereby sunlight can be captured to make chemical products. Inspired by the art of nature where leaves are able to collect enough sunlight to produce food, chemical engineers at Eindhoven University of Technology [&#8230;]<\/p>\n","protected":false},"author":59,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","nova_meta_subtitle":"","footnotes":""},"categories":[5572,5571],"tags":[12463,10743],"supplier":[19411,552],"class_list":["post-39685","post","type-post","status-publish","format-standard","hentry","category-bio-based","category-co2-based","tag-ccu2016","tag-useco2","supplier-angewandte-chemie-journal","supplier-technische-universiteit-eindhoven"],"_links":{"self":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/39685","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/users\/59"}],"replies":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/comments?post=39685"}],"version-history":[{"count":0,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/39685\/revisions"}],"wp:attachment":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media?parent=39685"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/categories?post=39685"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/tags?post=39685"},{"taxonomy":"supplier","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/supplier?post=39685"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}