{"id":36705,"date":"2016-08-18T07:20:03","date_gmt":"2016-08-18T05:20:03","guid":{"rendered":"https:\/\/rss.nova-institut.net\/public.php?url=http%3A%2F%2Fwww.biofuelsdigest.com%2Fbdigest%2F2016%2F08%2F14%2Famyris-the-new-colossus-aims-to-unlock-its-golden-door%2F"},"modified":"2016-08-16T13:20:45","modified_gmt":"2016-08-16T11:20:45","slug":"amyris-the-new-colossus-aims-to-unlock-its-golden-door","status":"publish","type":"post","link":"https:\/\/renewable-carbon.eu\/news\/amyris-the-new-colossus-aims-to-unlock-its-golden-door\/","title":{"rendered":"Amyris: The New Colossus aims to unlock its Golden Door"},"content":{"rendered":"<p>In California, Amyris reported a Q2 net loss of $13.8M on revenues of $9,6M, up from $7.8M in Q2 2015. Revenues rose 27% from the corresponding period in 2015 primarily driven by the shipment of a new novel fragrance product, as well as Neossance Squalane sales. At the same time, Amyris, which has recorded $18.4M in revenues for the first half, re-affirmed guidance for the year that it would reach $90M in annual sales and positive cash flow from operations in 2017.<\/p>\n<div>\n<p>With that, Amyris would have increased revenues by 400% in the second half, compared to the first half \u2014 so, a breakout for the company which was ranked last year as the #1 Hottest Company in the sector by the Digets\u2019s readers and international selectors.<\/p>\n<h4>The Seven Rays lighting\u00a0Amyris\u2019 Golden Lamp<\/h4>\n<p>Let\u2019s look at the 7 factors that have the company poised for a revenue transformation in the second half.<\/p>\n<p><strong>1. Gingko.<\/strong> Entered into an Initial Strategic Partnership Agreement with Ginkgo Bioworks to accelerate commercialization of bio-based ingredients and establish clear leadership in industrial biotechnology with a combined offering that we consider unparalleled. In connection with the agreement, a license fee of $15 million was paid on July 25, 2016, to Amyris in exchange for use of certain Amyris technology and the parties agreed to pursue the negotiation and execution of a definitive partnership agreement that includes significant value sharing. The partnership is expected to deliver more new ingredients into the global market over the next three years than the entire industry has achieved in the last 10 years.<\/p>\n<p>Melo pointed to the company\u2019s DARPA collaboration which has identified 400 different molecules, \u201call of which we can commercialize at our discretion.\u201d Also, 5th. Additional with Gingko, \u201cwe are already collaborating to align R&amp;D and take 70 products to the world\u2019s leading brands.\u201d<\/p>\n<p>Melo said that critical to Amyris growth will be \u201cmore capacity\u201d and the Amyris potential to \u201caccelerate products\u201d. Meanwhile, \u201cthe Brotas plant is running flat-out with farnesene production\u201d, the North Carolina facility too. The company has plans to double capacity at Brotas and is speaking with potential collaborators about potential expansions to increase capacity for 2017.<\/p>\n<p><strong>2. Cosmetics and personal care.<\/strong> Announced multi-year, multi-million-dollar collaboration in cosmetic active ingredients with Givaudan to engineer and produce cosmetic active targets for global commercialization by Givaudan. Amyris sees this partnership delivering an annual run rate $50M per year<\/p>\n<p><strong>3. Fragrance &amp; flavors<\/strong>. Began commercialization of novel fragrance product with Takasago International Corporation. The company said that it had greatly expanded in F&amp;F inovel fragrance ingredients, partnered with 4 of the top 5 companies, and is \u201con track to become one of key suppliers.\u201d<\/p>\n<p><strong>4. Jet fuel.<\/strong> Jointly announced with Cathay Pacific a two-year biojet agreement supporting continued strong farnesene demand and the future of sustainable air travel; initial flight on May 12, 2016 using the biojet blend was the longest flight using a renewable jet fuel to date. This fuel is supplied through the Amyris Total partnership that is dedicated to making BioJet an industrial reality.<\/p>\n<p><strong>5. Novvi.<\/strong> Announced American Refining Group\u2019s 33.3% equity investment in Novvi LLC, a joint venture of Amyris and Cosan S.A., enabling market access and acceleration in revenue growth of Novvi\u2019s high performance, sustainably sourced, renewable lubricants.<\/p>\n<p><strong>6. Janssen.<\/strong> Entered into research agreement with commercial license option with Janssen Biotech, facilitated by Johnson &amp; Johnson Innovation, to use Amyris\u2019s \u00b5Pharm platform for rapid integrated discovery and production of therapeutic compounds thereby opening a new area of compounds previously not accessible for new drug discovery. \u201cWe expect to sign one more collaboration by the end of the year, ending at the high-end of our range, to develop a library of natural and natural like of therapeutic compounds, which nature has the potential to provide and we have the ability to produce.\u201d<\/p>\n<p><strong>7. Biogen.<\/strong> Amyris nnounced partnership with Biogen, Inc. to develop alternative cell lines supporting production of therapeutics, marking second major partnership in biopharma market, which is now positioned to become Amyris\u2019s largest opportunity for collaborations. The Biogen partenrship is the most exciting of all,\u201d CEO John Melo said,. With it, Amyris he said would make \u201c a transformative change to biopharma where partner would be able to employ [Amyris biotechnology] instead of using cells from mammals. Others have attempted and failed, but we are positioned to deliver life saving therapeutics and make them more widely available. This could be game changing for biopharmaceuticals, and Biogen will fully fund the development.\u201d<\/p>\n<h4>Reaction from the Street<\/h4>\n<p>Jeffrey Osborne at Cowen &amp; Company wrote:<\/p>\n<p>Amyris reported revenues of $9.6 mn, coming in below both Cowen and Street estimates of $10.6 mn and $15.22 mn respectively due to timing of product shipments and collaboration payments.\u00a0 About 90% of its revenue for 2016 and about 70% of its revenue for 2017 [is] committed.<\/p>\n<p>Finally, the company expects continued growth from personal care as well as a significant ramp up in health and industrial segments in the second half, with ~33% coming from health, ~40% coming from personal care, and the rest coming from industrials. We are taking a wait and see approach given the uncertain pace of cost reductions. $1.25 price target.<\/p>\n<h4>The Bottom Line<\/h4>\n<p>Amyris started out in so many ways as a biopharma technology with the potential to radically transform, through synthetic biology, the potential to produce at radically lowered cost, and much bigger volume, a range of life-saving molecules. First was artemisinin, that has now been manufactured at commercial volumes for a couple of years now (primarily by Sanofi to date) as a low-cost malarial treatment. It was this aspect of Amyris technology that originally attracted the Bill &amp; Melinda Gates Foundation.<\/p>\n<p>Now, Amyris is back to the future, as it were. After a long tour through the potential for its technology to produce industrials, which has had spotty success due to price point, and a nascent effort to expand into personal care, which is small but promising \u2014 the company now sees 33% of its immediate growth coming from the health care sector.<\/p>\n<p>Next in importance is personal care \u2014 but we also are fascinated by the company potential in flavors &amp; fragrances. In short, a diversified portfolio \u2014 although the company is sharpening its portfolio and selling off \u201cnon-core assets\u201d, it is truly delivering on its original vision to have a balanced and broad product portfolio. Just farther up on the cost curve \u2014 generally excluding much of the expected fuels volume\u00a0\u2013 for now. That may change as oil prices rebound.<\/p>\n<p>The company says that with Gingko it will \u201ctake 70 products to the world\u2019s leading brands\u201d \u2014 and the time is nigh for that to unfold. Indeed, then the New Colossus will lift its lamp beside the Golden Door.<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In California, Amyris reported a Q2 net loss of $13.8M on revenues of $9,6M, up from $7.8M in Q2 2015. Revenues rose 27% from the corresponding period in 2015 primarily driven by the shipment of a new novel fragrance product, as well as Neossance Squalane sales. At the same time, Amyris, which has recorded $18.4M [&#8230;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","nova_meta_subtitle":"","footnotes":""},"categories":[5572],"tags":[6843,5796],"supplier":[2389,12480,8856,9441,8911,12481,4818,12482],"class_list":["post-36705","post","type-post","status-publish","format-standard","hentry","category-bio-based","tag-biochemicals","tag-biotechnology","supplier-amyris","supplier-biogen-inc","supplier-cathay-pacific-airways","supplier-ginkgo-bioworks","supplier-givaudan","supplier-janssen-biotech","supplier-novvi-sa","supplier-takasago-international-corporation"],"_links":{"self":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/36705","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/comments?post=36705"}],"version-history":[{"count":0,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/36705\/revisions"}],"wp:attachment":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media?parent=36705"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/categories?post=36705"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/tags?post=36705"},{"taxonomy":"supplier","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/supplier?post=36705"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}