{"id":34114,"date":"2016-04-06T07:25:34","date_gmt":"2016-04-06T05:25:34","guid":{"rendered":"https:\/\/renewable-carbon.eu\/news\/?p=34114"},"modified":"2016-04-05T13:41:17","modified_gmt":"2016-04-05T11:41:17","slug":"rub-researchers-use-cyanobacteria-for-the-production-of-chemicals","status":"publish","type":"post","link":"https:\/\/renewable-carbon.eu\/news\/rub-researchers-use-cyanobacteria-for-the-production-of-chemicals\/","title":{"rendered":"RUB researchers use cyanobacteria for the production of chemicals"},"content":{"rendered":"<p><strong>In order to manufacture chemical products in the industry, a high energy input is required, which consumes mainly our fossil resources. At RUB, two scientists are researching into a resource-efficient and, consequently, sustainable approach.<\/strong><\/p>\n<h3>Sustainable chemical processes<\/h3>\n<figure id=\"attachment_34112\" aria-describedby=\"caption-attachment-34112\" style=\"width: 210px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-34112 size-full\" src=\"https:\/\/renewable-carbon.eu\/news\/wp-content\/uploads\/2016\/04\/fittosize_210_0_fd3dd1f3905c806ce4ae134a71b5c820_2016_03_31-kourist_cyanobakterien_km.jpg\" alt=\"RUB; Cyanobakterien\" width=\"210\" height=\"140\" \/><figcaption id=\"caption-attachment-34112\" class=\"wp-caption-text\">Prof Dr Robert Kourist (left) and Dr Marc Nowaczyk with genetically modified cyanobacteria \u00a9 RUB, Marquard<\/figcaption><\/figure>\n<p>Prof Dr Robert Kourist from the junior research group Mikrobielle Biotechnologie and Dr Marc Nowaczyk from the Chair for Plant Biochemistry have succeeded in genetically modifying cyanobacteria, thus creating cells that produce enzymes for the manufacture of basic and fine chemicals. The bacteria also supply the energy required by the enzymes \u2013 by performing photosynthesis. A report on their work has been published in the renowned journal \u201cAngewandte Chemie\u201d.<\/p>\n<h3>No external supply of chemical energy necessary<\/h3>\n<p>To fulfil their function as biocatalysts, enzymes require chemical energy, which is typically supplied in form of sugar or other high-energy bonds. The researchers from Bochum, on the other hand, take advantage of the fact that, like plants, cyanobacteria perform photosynthesis. \u201cDuring photosynthesis, light energy is initially converted into chemical energy. In the second step, that energy is mainly used for binding of carbon dioxide. However, a small percentage of the energy remains and can be directly utilised,\u201d says Marc Nowaczyk. The approach adopted by the researchers is to decouple the supplied chemical energy from carbon fixation and to use it directly for chemical reactions.<\/p>\n<h3>No unwanted by-products<\/h3>\n<p>Using genetically modified living cyanobacteria as catalysts for photosynthesis driven biotransformations is a new approach. As the researchers point out, they have observed that cyanobacteria catalyse only the synthesis of the desired chemical product in their experiments and, consequently, that they function selectively. Many catalytic processes produce not just one product, but also a mirrored one, which has to be painstakingly filtered out. \u201cThe outstanding selectivity is crucial for deployment in industrial applications,\u201d says Robert Kourist.<\/p>\n<h3>Broad application range<\/h3>\n<p>The experiments have, moreover, demonstrated that enzymes from other organisms can be successfully introduced into cyanobacteria. This means that the process can be used in a number of reactions. \u201cThe chemical industry has to become cleaner,\u201d as Robert Kourist sums up the researchers&#8217; ambitious objective. Utilising photosynthesis to catalyse chemical reactions is a promising step towards this aim.<\/p>\n<p>&nbsp;<\/p>\n<h3>Original publication<\/h3>\n<p>K. K\u00f6ninger, A. Gomez-Baraibar, C. M\u00fcgge, C. Paul., F. Hollmann, M. Nowaczyk, R. Kourist (2016): Recombinant cyanobacteria as tools for asymmetric C=C bond reduction fueled by biocatalytic water oxidation, Angewandte Chemie, DOI: <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201601200\/full\" target=\"_blank\">10.1002\/anie.201601200R201601201<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In order to manufacture chemical products in the industry, a high energy input is required, which consumes mainly our fossil resources. At RUB, two scientists are researching into a resource-efficient and, consequently, sustainable approach. Sustainable chemical processes Prof Dr Robert Kourist from the junior research group Mikrobielle Biotechnologie and Dr Marc Nowaczyk from the Chair [&#8230;]<\/p>\n","protected":false},"author":59,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","nova_meta_subtitle":"","footnotes":""},"categories":[5572],"tags":[6843],"supplier":[19411,1806],"class_list":["post-34114","post","type-post","status-publish","format-standard","hentry","category-bio-based","tag-biochemicals","supplier-angewandte-chemie-journal","supplier-ruhr-universitaet-bochum"],"_links":{"self":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/34114","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/users\/59"}],"replies":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/comments?post=34114"}],"version-history":[{"count":0,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/34114\/revisions"}],"wp:attachment":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media?parent=34114"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/categories?post=34114"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/tags?post=34114"},{"taxonomy":"supplier","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/supplier?post=34114"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}