{"id":163261,"date":"2025-05-22T07:23:00","date_gmt":"2025-05-22T05:23:00","guid":{"rendered":"https:\/\/renewable-carbon.eu\/news\/?p=163261"},"modified":"2025-05-20T10:40:45","modified_gmt":"2025-05-20T08:40:45","slug":"starch-based-microplastics-could-cause-health-risks-in-mice-study-finds","status":"publish","type":"post","link":"https:\/\/renewable-carbon.eu\/news\/starch-based-microplastics-could-cause-health-risks-in-mice-study-finds\/","title":{"rendered":"Starch-based microplastics could cause health risks in mice, study finds"},"content":{"rendered":"\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright\"><img decoding=\"async\" src=\"https:\/\/www.acs.org\/content\/acs\/en\/pressroom\/presspacs\/2025\/april\/starch-based-microplastics-could-cause-health-risks-in-mice\/_jcr_content\/mainContent\/textimage_copy\/image.scale.medium.1399.jpg\/1744052273379.jpg\" alt=\"Two sets of disposable cutlery made from starch-based plastic.\"\/><figcaption class=\"wp-element-caption\">Microscopic fragments from starch-based plastics (similar to those shown here) caused negative health impacts in mice, including changes to organ tissues, metabolic functions and gut microbiota diversity. \u00a9 Kononov Oleh\/Shutterstock.com<\/figcaption><\/figure><\/div>\n\n\n<p><strong>Wear and tear on plastic products releases small to nearly invisible plastic particles, which could impact people\u2019s health when consumed or inhaled. To make these particles biodegradable, researchers created plastics from plant starch instead of petroleum.<a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.4c10855\"> An initial study published in ACS\u2019&nbsp;<em>Journal of Agricultural and Food Chemistry<\/em>&nbsp;<\/a>shows how animals consuming particles from this alternative material developed health problems such as liver damage and gut microbiome imbalances.<\/strong><\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>\u201cBiodegradable starch-based plastics may not be as safe and health-promoting as originally assumed,\u201d says <strong>Yongfeng Deng, the corresponding author of the study.<\/strong><\/p>\n<\/blockquote>\n\n\n\n<p>Microplastics (plastic pieces less than 5 millimeters wide) are entering human bodies through contaminated water supplies, foods and drinks \u2014 and&nbsp;<a href=\"https:\/\/www.acs.org\/pressroom\/presspacs\/2025\/march\/medical-infusion-bags-can-release-microplastics.html\">even IV infusions<\/a>. Scientists have linked plastic particles in the bloodstream and tissues to various health risks. For example, a study found that&nbsp;<a href=\"https:\/\/www.acs.org\/pressroom\/newsreleases\/2021\/december\/people-with-ibd-have-more-microplastics-in-their-feces-study-says.html\">people with inflammatory bowel disease have more microplastics in their feces<\/a>. Biodegradable plastics have been presented as a safer, more environmentally friendly alternative to traditional petroleum-based plastics. One of the most common types comes from starch, a carbohydrate found in potatoes, rice and wheat. However, there is a lack of information on how starch-based biodegradable plastics affect the body. A team of researchers led by Deng tackled this issue by exploring these effects in animal trials.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"252\" src=\"https:\/\/renewable-carbon.eu\/news\/media\/2025\/05\/jf4c10855_0007.webp\" alt=\"\" class=\"wp-image-163328\" srcset=\"https:\/\/renewable-carbon.eu\/news\/media\/2025\/05\/jf4c10855_0007.webp 500w, https:\/\/renewable-carbon.eu\/news\/media\/2025\/05\/jf4c10855_0007-300x151.webp 300w, https:\/\/renewable-carbon.eu\/news\/media\/2025\/05\/jf4c10855_0007-150x76.webp 150w, https:\/\/renewable-carbon.eu\/news\/media\/2025\/05\/jf4c10855_0007-400x202.webp 400w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><figcaption class=\"wp-element-caption\">\u00a9 ACS<\/figcaption><\/figure><\/div>\n\n\n<p>The researchers compared three groups of five mice: one group consuming normal chow and two groups consuming food infused with starch-based microplastics. The doses (low and high) were calculated and scaled from what an average human is expected to consume daily. They fed the mice for 3 months and then assessed the animals\u2019 organ tissues, metabolic functions and gut microbiota diversity. Mice exposed to the starch-based plastic particles had:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Multiple damaged organs, including the liver and ovaries, with more pronounced damage in the high-dose group. However, mice eating normal chow showed normal organ tissue biopsies.&nbsp;<\/li>\n\n\n\n<li>Altered glucose management, including significant abnormality in triglycerides (a type of fat) and disruption in molecular biomarkers associated with glucose and lipid metabolism, compared to mice fed normal chow.&nbsp;<\/li>\n\n\n\n<li>Dysregulated genetic pathways and specific gut microbiota imbalances, which the researchers suggest could alter microplastic-consuming animals\u2019 circadian rhythms.<\/li>\n<\/ul>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>\u201cProlonged low-dose exposure to starch-based microplastics can lead to a broad spectrum of health impacts, particularly perturbing circadian rhythms and disrupting glucose and lipid metabolism,\u201d says <strong>Deng.<\/strong> <\/p>\n<\/blockquote>\n\n\n\n<p>However, the researchers acknowledge that because this is one of the first studies examining the impacts of consuming starch-based microplastics, further research is needed to understand how these biodegradable particles break down in the body.&nbsp;<\/p>\n\n\n\n<p><em>The authors acknowledge funding from the Natural Science Foundation of China, the Jiangsu Province<\/em><\/p>\n\n\n\n<p><em>Young Science and Technology Talent Support Program, the Joint Fund of Departments and Schools, the Start-up Research Fund, and the Zhishan Young Scholars Fund of Southeast University by the Fundamental Research Funds for the Central Universities.<\/em><\/p>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">About the American Chemical Society<\/h3>\n\n\n\n<p>The American Chemical Society (ACS) is a nonprofit organization founded in 1876 and chartered by the U.S. Congress. ACS is committed to improving all lives through the transforming power of chemistry. Its mission is to advance scientific knowledge, empower a global community and champion scientific integrity, and its vision is a world built on science. The Society is a global leader in promoting excellence in science education and providing access to chemistry-related information and research through its multiple research solutions, peer-reviewed journals, scientific conferences, e-books and weekly news periodical&nbsp;<em>Chemical &amp; Engineering News<\/em>. ACS journals are among the most cited, most trusted and most read within the scientific literature; however, ACS itself does not conduct chemical research. As a leader in scientific information solutions, its CAS division partners with global innovators to accelerate breakthroughs by curating, connecting and analyzing the world\u2019s scientific knowledge. ACS\u2019 main offices are in Washington, D.C., and Columbus, Ohio.<\/p>\n\n\n\n<p>Registered journalists can subscribe to the&nbsp;<a href=\"https:\/\/www.eurekalert.org\/press\/acspress\/home\">ACS journalist news portal on EurekAlert!<\/a>&nbsp;to access embargoed and public science press releases. For media inquiries, contact&nbsp;<a href=\"mailto:newsroom@acs.org\">newsroom@acs.org<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wear and tear on plastic products releases small to nearly invisible plastic particles, which could impact people\u2019s health when consumed or inhaled. To make these particles biodegradable, researchers created plastics from plant starch instead of petroleum. An initial study published in ACS\u2019&nbsp;Journal of Agricultural and Food Chemistry&nbsp;shows how animals consuming particles from this alternative material [&#8230;]<\/p>\n","protected":false},"author":59,"featured_media":163329,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"none","nova_meta_subtitle":"\u201cLong-Term Exposure to Environmentally Realistic Doses of Starch-Based Microplastics Suggests Widespread Health Effects\u201d - Journal of Agricultural and Food Chemistry","footnotes":""},"categories":[5572],"tags":[11270,5847,10416,10954],"supplier":[1143,26362,26361,24253],"class_list":["post-163261","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bio-based","tag-biodegradability","tag-bioplastics","tag-circulareconomy","tag-microplastics","supplier-american-chemical-society-acs","supplier-jiangsu-ocean-university-jou","supplier-jinan-university","supplier-southeast-university"],"_links":{"self":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/163261","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/users\/59"}],"replies":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/comments?post=163261"}],"version-history":[{"count":0,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/163261\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media\/163329"}],"wp:attachment":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media?parent=163261"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/categories?post=163261"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/tags?post=163261"},{"taxonomy":"supplier","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/supplier?post=163261"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}