In Tennessee, a team led by Pratul Agarwal of the Department of Energy\u2019s Oak Ridge National Laboratory have discovered that light of specific wavelengths can be used to boost an enzyme\u2019s function by as much as 30 fold, potentially establishing a path to less expensive biofuels, detergents and a host of other products.<\/b><\/p>\n
The researchers introduced a light-activated molecular switch across two regions of the enzyme Candida antarctica lipase B, or CALB \u2013 which breaks down fat molecules \u2014 identified through modeling performed on DOE\u2019s Jaguar supercomputer.<\/p>\n
“Using this approach, our preliminary work with CALB suggested that such a technique of introducing a compound that undergoes a light-inducible conformational change onto the surface of the protein could be used to manipulate enzyme reaction,\u201d Agarwal said. The team\u2019s “Engineering a Hyper-catalytic Enzyme by Photoactivated Conformation Modulation,\u201d is available here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":" In Tennessee, a team led by Pratul Agarwal of the Department of Energy’s Oak Ridge National Laboratory have discovered that light of specific wavelengths can<\/b><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","nova_meta_subtitle":"","footnotes":""},"categories":[5572],"tags":[],"supplier":[2437],"class_list":["post-15723","post","type-post","status-publish","format-standard","hentry","category-bio-based","supplier-oak-ridge-national-laboratory"],"_links":{"self":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/15723","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/comments?post=15723"}],"version-history":[{"count":0,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/15723\/revisions"}],"wp:attachment":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media?parent=15723"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/categories?post=15723"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/tags?post=15723"},{"taxonomy":"supplier","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/supplier?post=15723"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}