{"id":148717,"date":"2024-07-26T07:05:00","date_gmt":"2024-07-26T05:05:00","guid":{"rendered":"https:\/\/renewable-carbon.eu\/news\/?p=148717"},"modified":"2024-07-25T14:06:05","modified_gmt":"2024-07-25T12:06:05","slug":"biotechnological-approaches-for-producing-natural-pigments-in-yeasts","status":"publish","type":"post","link":"https:\/\/renewable-carbon.eu\/news\/biotechnological-approaches-for-producing-natural-pigments-in-yeasts\/","title":{"rendered":"Biotechnological approaches for producing natural pigments in yeasts"},"content":{"rendered":"\n\n\n

Natural pigments are increasingly in demand over synthetic pigments due to their beneficial biological activities and environmentally friendly process.<\/strong><\/p>\n\n\n

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\"An
An elevated view of color powder in the different type of bowls on concrete backdrop. Image by freepik \u00a9 freepik<\/figcaption><\/figure><\/div>\n\n\n

Recent advances in metabolic engineering and synthetic biology enabled the sustainable bioproduction of natural pigments from microorganisms.<\/p>\n\n\n\n

Metabolic engineering strategies, including modulation of metabolic flux, enzyme engineering, subcellular compartmentalization, and co-cultures, allowed the improvement in production of natural pigments from yeasts.<\/p>\n\n\n\n

Optimization of fermentation and downstream process helped to achieve high titer and yield of target pigment compounds.<\/p>\n\n\n\n

System-based engineering strategies, a quantitative assessment of sustainability, and a quality analysis of pigments will contribute to accelerate the commercialization of bio-based pigments.<\/p>\n\n\n\n

Abstract<\/h3>\n\n\n\n

Pigments are widely used in the food, cosmetic, textile, pharmaceutical, and materials industries. Demand for natural pigments has been increasing due to concerns regarding potential health problems and environmental pollution from synthetic pigments. Microbial production of natural pigments is a promising alternative to chemical synthesis or extraction from natural sources. Here, we discuss yeasts as promising chassis for producing natural pigments with their advantageous traits such as genetic amenability, safety, rapid growth, metabolic diversity, and tolerance. Metabolic engineering strategies and optimizing strategies in downstream process to enhance production of natural pigments are thoroughly reviewed. We discuss the challenges, including expanding the range of natural pigments and improving their feasibility of industrial scale-up, as well as the potential strategies for future development.<\/p>\n\n\n\n

DOI: https:\/\/doi.org\/10.1016\/j.tibtech.2024.06.012<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Natural pigments are increasingly in demand over synthetic pigments due to their beneficial biological activities and environmentally friendly process. Recent advances in metabolic engineering and synthetic biology enabled the sustainable bioproduction of natural pigments from microorganisms. Metabolic engineering strategies, including modulation of metabolic flux, enzyme engineering, subcellular compartmentalization, and co-cultures, allowed the improvement in production […]<\/p>\n","protected":false},"author":114,"featured_media":148719,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"none","nova_meta_subtitle":"Pigments are widely used in the food, cosmetic, textile, pharmaceutical, and materials industries","footnotes":""},"categories":[5572],"tags":[5838,14709,5796,14173,13821],"supplier":[14693,17659,20426],"class_list":["post-148717","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bio-based","tag-bioeconomy","tag-bioproduction","tag-biotechnology","tag-pigments","tag-yeast","supplier-agroparistech","supplier-inrae","supplier-universite-paris-saclay"],"_links":{"self":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/148717","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/users\/114"}],"replies":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/comments?post=148717"}],"version-history":[{"count":0,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/148717\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media\/148719"}],"wp:attachment":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media?parent=148717"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/categories?post=148717"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/tags?post=148717"},{"taxonomy":"supplier","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/supplier?post=148717"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}