{"id":129132,"date":"2023-07-13T07:18:00","date_gmt":"2023-07-13T05:18:00","guid":{"rendered":"https:\/\/renewable-carbon.eu\/news\/?p=129132"},"modified":"2023-07-10T09:51:42","modified_gmt":"2023-07-10T07:51:42","slug":"scientists-make-common-pain-killers-from-pine-trees-instead-of-crude-oil","status":"publish","type":"post","link":"https:\/\/renewable-carbon.eu\/news\/scientists-make-common-pain-killers-from-pine-trees-instead-of-crude-oil\/","title":{"rendered":"Scientists make common pain killers from pine trees instead of crude oil"},"content":{"rendered":"\n\n\n

A team of scientists, from the University of Bath\u2019s Department of Chemistry and\u00a0Institute for Sustainability<\/a>\u00a0have found a way to create two of the world\u2019s most common painkillers, paracetamol and ibuprofen, out of a compound found in pine trees, which is also a waste product from the paper industry.<\/strong><\/p>\n\n\n\n

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Many drugs like paracetamol and ibuprofen are made using crude oil products, which is unsustainable. \u00a9<\/strong> H_Ko<\/figcaption><\/figure><\/div>\n\n\n\n

It is perhaps not widely known that many common pharmaceuticals are manufactured using chemical precursors derived from crude oil, presenting a niche sustainability challenge as the world targets Net Zero. <\/p>\n\n\n\n

The research team from Bath has developed a method of creating a range of pharmaceutical precursors from biorenewable \u03b2-pinene, a component of turpentine which is a waste by-product from the paper industry (annual production >350,000 tonnes).<\/p>\n\n\n\n

They successfully converted \u03b2-pinene into two everyday painkillers, paracetamol and ibuprofen, which are produced on ~100,000 tonne scales annually. <\/p>\n\n\n\n

They also successfully synthesised a range of other precursor chemicals from turpentine, including 4-HAP (4-hydroxyacetophenone), which is the precursor of drugs including beta-blockers and the asthma inhaler drug, salbutamol, as well as others widely used for perfumes and in cleaning products.<\/p>\n\n\n\n

They hope that this more sustainable \u201cbiorefinery\u201d approach could replace the need for crude oil products in the chemical industry.<\/p>\n\n\n\n

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Conversion of \u03b2-pinene into paracetamol and ibuprofen \u00a9<\/strong> University of Bath<\/figcaption><\/figure><\/div>\n\n\n\n

Dr Josh Tibbetts, Research Associate in the University\u2019s Department of Chemistry, said: \u201cUsing oil to make pharmaceuticals is unsustainable \u2013 not only is it contributing to rising CO\u2082 emissions, but the price fluctuates dramatically as we are greatly dependent on the geopolitical stability of countries with large oil-reserves, and it is only going to get more expensive.<\/p>

\u201cInstead of extracting more oil from the ground, we want to replace this in the future with a \u2018bio-refinery\u2019 model.<\/p>

\u201cOur turpentine-based biorefinery model uses waste chemical by-products from the paper industry to produce a spectrum of valuable, sustainable chemicals that can be used in a wide range of applications from perfumes to paracetamol.\u201d<\/p><\/blockquote>\n\n\n\n

Instead of putting chemicals in a large reactor to create separate batches of product, the method uses continuous flow reactors, meaning production can be uninterrupted and easier to scale up.<\/p>\n\n\n\n

Whilst the process in its current form may be more expensive than using oil-based feedstocks, consumers may be prepared to pay a slightly higher price for more sustainable pharmaceuticals that are completely plant-derived.<\/p>\n\n\n\n

The research, funded by the Engineering and Physical Sciences Research Council, is published in the journal\u00a0ChemSusChem<\/em><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

A team of scientists, from the University of Bath\u2019s Department of Chemistry and\u00a0Institute for Sustainability\u00a0have found a way to create two of the world\u2019s most common painkillers, paracetamol and ibuprofen, out of a compound found in pine trees, which is also a waste product from the paper industry. It is perhaps not widely known that […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"none","nova_meta_subtitle":"Common drugs such as paracetamol and ibuprofen can be made from a chemical from pine trees instead of crude oil products","footnotes":""},"categories":[5572],"tags":[15836,5831,22058,16432,14859],"supplier":[8192,1170],"class_list":["post-129132","post","type-post","status-publish","format-standard","hentry","category-bio-based","tag-biomedicine","tag-biorefinery","tag-biorenewable","tag-medicine","tag-plantbased","supplier-chemsuschem","supplier-university-of-bath"],"_links":{"self":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/129132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/comments?post=129132"}],"version-history":[{"count":0,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/posts\/129132\/revisions"}],"wp:attachment":[{"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/media?parent=129132"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/categories?post=129132"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/tags?post=129132"},{"taxonomy":"supplier","embeddable":true,"href":"https:\/\/renewable-carbon.eu\/news\/wp-json\/wp\/v2\/supplier?post=129132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}