LEGO\u00ae bricks constitute a building ecosystem that can be used by the general public, science researchers, and engineers to design and assemble systems of all kinds. The variety of LEGO\u00ae creations from the general public, ranging from artwork to automated systems, demonstrate the versatility and quality of LEGO\u00ae systems. In parallel, an increasing number of custom LEGO\u00ae systems for science are designed to fulfill the specific requirements of experimental scientists from all fields.<\/p>\n\n\n\n
LEGO\u00ae is a brand of toys that have entertained generations of children. Beyond amusement, LEGO\u00ae bricks also constitute a building ecosystem of their own that creators from the general public, as well as scientists and engineers, can use to design and assemble devices for all purposes, including scientific research and biotechnology. We describe several of these constructions to highlight the construction properties of LEGO\u00ae and their advantages, caveats, and impact in biotechnology. We also discuss how this emerging trend in LEGO\u00ae building pairs with a growing interest in open-access and frugal science which aims to provide access to technology to all scientists regardless of financial wealth and technological prowess.<\/p>\n\n\n\n